Advanced DNA Analysis Techniques

GETTING MORE OUT OF GENETIC GENEALOGY RESEARCH: INTERMEDIATE TO ADVANCED DNA ANALYSIS TECHNIQUES

Course Coordinators:

 

CeCe Moore
Angiel Bush, MS
 
Course Instructors:
CeCe Moore
Angie Bush, MS
Blaine Bettinger, Ph.D., J.D.

This advanced analysis course is intended for the genealogist who has a thorough understanding of genetic genealogy basics and has experience applying DNA testing to family history research. This is the next step in genetic genealogy education, with a focus on preparing professionals and others to work on genetic genealogy cases and strengthen the skills of those who are already doing so.

 

This course will examine the methods used by expert genetic genealogists to thoroughly and accurately analyze DNA testing results to advance knowledge of an individual’s genealogy. Instruction will include complex case studies that incorporate multiple types of DNA testing results, analyzed in conjunction with documentary evidence, as well as cases where DNA test results are the primary resource, such as in unknown parentage cases. Coursework will include analyzing and comparing DNA testing data from all of the companies offering products to the genealogy community with explanations and demonstrations of the most valuable features and tools for the genetic genealogist working with large amounts of data. Through active participation in and completion of this course, the genealogist will gain essential skills for integrating DNA testing with traditional genealogy research on an advanced level. 
 
Note that this course is advanced and as such has the following prerequisite requirements. If you do not meet one of the three below you may write an essay detailing why you should still be allowed to take the course.
 
Pre-Requisites:
 
This class will move very quickly and assume attendees have an excellent understanding of many foundational concepts. Please take the course entitled "Getting Started with Genetic Genealogy" if you do not meet at least one of these three requirements:
 
1. Completion of Genetic Genealogy course offered through GRIP in July 2014
2. Completion of the autosomal DNA methodology class offered through DNA Adoption
3. All three of the following:
a) DNA testing - you must have completed or had a family member complete all three types of DNA testing (yDNA, mtDNA and atDNA). In the case of the direct line tests, you must be a member of the corresponding surname and/or haplogroup projects. You do not need to administer a surname or haplogroup project - AND
b) Testing Companies - You or a close family member and/or client must have completed autosomal DNA testing with two of the three major companies. These companies are AncestryDNA, Family Tree DNA and 23andMe. You should be very familiar with the web interfaces for these companies - AND
c) You must be actively using DNA as a "record type" in solving a question of a genealogical nature. This question can be for your own genealogical research or for that of a client.
 
If you have any questions regarding your qualifications for this course, please email course coordinators at info@thednadetectives.com
 
Overview
 
This advanced analysis course is intended for the genealogist who has a thorough understanding of genetic genealogy basics and has experience applying DNA testing to family history research. This is the next step in genetic genealogy education, with a focus on preparing professionals and others to work on genetic genealogy cases and strengthen the skills of those who are already doing so.
 
This course will examine the methods used by expert genetic genealogists to thoroughly and accurately analyze DNA testing results to advance knowledge of an individual’s genealogy. Instruction will include complex case studies that incorporate multiple types of DNA testing results, analyzed in conjunction with documentary evidence, as well as cases where DNA test results are the primary resource, such as in unknown parentage cases. 
 
Coursework will include analyzing and comparing DNA testing data from all of the companies offering products to the genealogy community with explanations and demonstrations of the most valuable features and tools for the genetic genealogist working with large amounts of data. Through active participation in and completion of this course, the genealogist will gain essential skills for integrating DNA testing with traditional genealogy research on an advanced level.
 
Course Outline/Descriptions
 
DNA Tests and Testing Companies
• Review of the four types of DNA found in our cells. 
• Meiosis and recombination.
• Inheritance patterns for each type of DNA.
• DNA testing companies and their products (mention STR based autosomal, Geno 2.0, Full Genomes, Britain’s DNA and FTDNA’s European affiliates in addition to the “big three” – help attendees understand what a certain test is if a client or other person comes to them asking about one of these companies and their testing options)
 
Advanced Terminology and Concepts
• In depth explanations for terms such as haplogroup, haplotype, heteroplasmy, STR, SNP, centromere and telomere, etc. 
• Understanding reference sequences (Human Genome) in conjunction with DNA results Advanced Y-DNA Testing
• STR vs SNP based tests
• Surname and haplogroup projects
• Available testing options – Big Y, Chromo 2, Full-Genomes, Geno 2.0
• Current and future application of advanced tests to genealogical research
• Third party tools and websites for Y-DNA testing (include the companies/people that are offering analysis.)